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肺癌化疗中，由于多药耐药（multidrugresistance，MDR）的产生，导致许多肺癌患者化疗失败。阿霉素（ADM）、长春新碱（VCR）、鬼臼乙叉甙（Vp－１６）等所介导的耐药为多药耐药。已证实三苯氧胺（tamoxifen，TAM）有逆转肿瘤多药耐药的作用犤１，２犦。三氟拉嗪（trifluopera
In chemotherapy for lung cancer, many patients with lung cancer fail chemotherapy because of multidrug resistance (MDR). The drug resistance mediated by adriamycin (ADM), vincristine (VCR), and etoposide (Vp-16) is multidrug resistance. Tamoxifen (TAM) has been shown to reverse the effects of multidrug resistance in tumors (1, 2). Trifluoperazine (trifluopera