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目的:比较急性胰腺炎(AP)患者的强离子隙(SIG)、动脉血钙离子(ABC)、血糖(BG)等指标与其预后的相关性。方法:回顾性研究2014-01-2014-12我院救治的130例AP患者,根据预后将其分为生存组和死亡组,比较2组患者AP早期SIG、ABC、BG等指标水平及其他一般资料结果,并通过分析病死率OR值和建立受试者工作特征(ROC)曲线,比较SIG、ABC、BG等指标对AP患者预后的有效性。结果:SIG值>9的患者死亡风险明显高于SIG值≤9的患者,ABC≤0.9 mmol/L的患者死亡风险高于ABC>0.9 mmol/L的患者,BG≤13mmol/L的患者死亡风险低于BG>13 mmol/L的患者(P<0.05),SIG病死率OR值明显高于ABC和BG(P<0.05)。在ROC曲线中,SIG、ABC、BG预测AP患者死亡的曲线下面积分别为0.812、0.699、0.606。结论:早期SIG、BG水平升高以及ABC水平降低将增加AP患者的死亡风险,且早期的SIG水平对AP患者的死亡风险预测较BG和ABC更加准确,值得临床上进一步应用和研究。
OBJECTIVE: To compare the correlations between strong ion gap (SIG), arterial calcium (BG), blood glucose (BG) and prognosis in patients with acute pancreatitis (AP). Methods: A retrospective study of 130 AP patients treated in our hospital from January 2014 to December 2014 was divided into survival group and death group according to the prognosis. The levels of SIG, ABC, BG and other indicators in the early stage of AP were compared between the two groups Data analysis, and through the analysis of mortality OR and establishment of receiver operating characteristic (ROC) curve, comparing the SIG, ABC, BG and other indicators of the prognosis of AP patients. Results: The death risk of patients with SIG> 9 was significantly higher than that of patients with SIG ≤9. The risk of death in patients with ABC≤0.9 mmol / L was higher than that in patients with ABC> 0.9 mmol / L, and the risk of death in patients with BG≤13 mmol / L The OR of SIG mortality was significantly higher than that of ABC and BG (P <0.05) in patients with BG> 13 mmol / L (P <0.05). In the ROC curve, the area under the curve of SIG, ABC and BG predicting the death of AP patients were 0.812, 0.699 and 0.660, respectively. CONCLUSION: Elevated SIG and BG levels in the early stage and decreased ABC levels will increase the risk of death in patients with AP. The early stage of SIG level is more accurate in predicting the death risk of patients with AP than BG and ABC, which is worth further clinical application.