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目的探讨2006—2013年25例输入性恶性疟的流行特征及临床诊断和治疗效果。方法回顾性分析恶性疟病例的流行病学资料及临床资料。结果 25例恶性疟病例均有蚊虫叮咬史和有非洲地区居留史,临床症状主要为发热、畏寒、大汗、呕吐、贫血、血小板数减少、和肝肾功能异常等。在蒿甲醚联合伯氨喹治疗后,25例恶性疟均获痊愈,无输入性恶性疟传播。结论菏泽市输入性恶性疟以有非洲旅居史,青年、中年男性为主,近年来发病有所增加;恶性疟诊断主要依靠反复外周血涂片检测;蒿甲醚联合伯氨喹治疗方案治疗效果可靠。
Objective To investigate the epidemiological characteristics, clinical diagnosis and treatment of imported falciparum malaria in 25 cases from 2006 to 2013. Methods The epidemiological data and clinical data of falciparum malaria cases were retrospectively analyzed. Results All the 25 cases of falciparum malaria had history of mosquito bites and residence in Africa. The main clinical symptoms were fever, chills, sweating, vomiting, anemia, reduction of platelet count, and abnormal liver and kidney function. After treatment with artemether and primaquine, 25 cases of falciparum malaria were cured without any transmission of imported falciparum malaria. Conclusion The imported malaria in Heze is mainly living in Africa, young and middle-aged males. The incidence of malaria in Heze City has been increased in recent years. The diagnosis of P. falciparum mainly depends on the repeated smear of peripheral blood smear, the treatment of artemether combined with primaquine Reliable results.