由于动物试验表明肼是一种诱变剂和致癌物,人们对药物中肼的存在十分关注,因此现在肼的测定已经延伸到肼苯哒嗪,肼苯哒嗪中肼的沾污发生于合成过程或由于药物降解。本文研究了一种测定肼苯哒嗪和异烟肼原料、单、复方片剂、注射剂和糖浆剂中肼的GLC法,该法基于肼与苯甲醛生成苄连氮,最低检测浓度为～0.0003％。 Since animal tests show that hydrazine is a mutagen and a carcinogen, much attention has been paid to the presence of hydrazine in the drug, and as a result hydrazine has now been extended to hydralazine, hydrazine contamination in hydralazine occurs in the synthesis Process or due to drug degradation. In this paper, a method for the determination of hydralazine and isoniazid raw materials, single, compound tablets, injection and syrup hydrazine GLC method, the method based on hydrazine and benzaldehyde generated benzidine, the lowest detection concentration of ~ 0.0003 %.