自1958年Barraquer倡议用甲糜蛋白酶行白内障囊内摘出术以来,各地采用后,认为是近年来眼科手术的一项进展。但Weekers等则认为甲糜蛋白酶能导致严重的永久性线状角膜炎、大量的虹膜色素脱落、玻璃状体破裂、继发性青光眼及视网膜脱离等并发症。后来Barra Since the Barraquer initiative in 1958, the use of chymotrypsin for intraocular cataract extraction has become a major advance in ophthalmic surgery in recent years. However, Weekers et al. Argue that chymotrypsin can cause severe permanent keratitis, a large number of iris pigmentation, vitreous body rupture, secondary glaucoma and retinal detachment and other complications. Later Barra