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目的:对急性脑梗死静脉溶栓治疗的预后效果进行分析和探讨。方法:选取急性脑梗死患者70例,对临床治疗资料进行回顾性分析,根据发病至治疗时间分为ABC3组,其中A组为3h内,B组为6h内,C组为超过6h。AB两组给予静脉溶栓治疗,C组给予常规治疗。对比三组患者治疗的预后效果。结果:和治疗前相比,AB两组的神经功能损伤(NDS)评分均有显著下降,C组评分治疗后2周有所下降(P<0.05)。治疗前各组评分差异无统计学意义(P>0.05),治疗后各组之间差异均具有统计学意义(P<0.05)。同时ABC各组的有效率分别为83.33%、73.07%、60%,各组的组间差异均具有统计学意义(P<0.05)。另外,三组的出血率分别为12.5%、15.38%和5%,常规治疗的出血率低于静脉溶栓(P<0.05)。结论:对急性脑梗死患者越早进行静脉溶栓治疗,其效果就更显著,预后更好。
Objective: To analyze and discuss the prognosis of thrombolytic therapy of acute cerebral infarction. Methods: A total of 70 patients with acute cerebral infarction were enrolled in this study. The data of clinical treatment were retrospectively analyzed. According to the time from onset to treatment, they were divided into ABC3 group, in which group A was within 3h, group B within 6h and group C over 6h. AB two groups given intravenous thrombolytic therapy, C group given conventional treatment. The prognosis of the three groups was compared. Results: Compared with those before treatment, the scores of neurological impairment (NDS) in both groups decreased significantly. The score of C group decreased after two weeks (P <0.05). Before treatment, there was no significant difference between the groups (P> 0.05). After treatment, the differences among the groups were statistically significant (P <0.05). At the same time, the efficacies of ABC in each group were 83.33%, 73.07% and 60%, respectively. The differences among groups were statistically significant (P <0.05). In addition, the bleeding rates of the three groups were 12.5%, 15.38% and 5%, respectively, and the bleeding rate of conventional treatment was lower than that of intravenous thrombolysis (P <0.05). Conclusion: The sooner the patients with acute cerebral infarction are treated with intravenous thrombolysis, the effect is more significant and the prognosis is better.