人参皂苷(Ginsenoside)是人参、西洋参、三七的主要活性成分之一,具有极强的生理活性,逐渐成为国内外研究的热点。在肾脏具有抗氧化应激、抗纤维化、改善微循环、抑制血小板聚集、Ca2+拮抗、提高免疫等作用。因此,研究人参皂苷单体的活性及作用机制对肾脏病临床应用有重大意义。 Ginsenoside is one of the main active components of ginseng, American ginseng and Panax notoginseng and has strong physiological activity. It has become a hot research field at home and abroad. In the kidney with anti-oxidative stress, anti-fibrosis, improve microcirculation, inhibition of platelet aggregation, Ca2 antagonism, improve immunity and so on. Therefore, the study of ginsenoside monomer activity and mechanism of action for the clinical application of kidney disease is of great significance.