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目的:探讨重度子痫前期终止妊娠的时机与方式。方法:回顾性分析2000～2007年江西省宜春市人民医院159例重度子痫前期患者的孕周及分娩方式与围产儿预后的关系。结果:32～36+6周出生的新生儿低体重发生率明显高于孕37周以后出生者(P<0.01),肺透明膜病发生率与孕37周以后出生者存在差异(P<0.05),但围产儿存活率与孕37周后出生者比较无明显差异(P>0.05)。孕37周以后出生者的新生儿窒息率及吸入性肺炎的发生率均明显高于孕32～36+6周出生者(P<0.05),阴道分娩与剖宫产的围生儿预后无明显差异(P>0.05)。结论:重度子痫前期患者经积极治疗无明显好转者可在孕32～36+6周考虑终止妊娠;孕周≥37周者无论病情及治疗效果如何,均应尽早终止妊娠,适当选择阴道分娩并不增加母婴危险性。
Objective: To investigate the timing and manner of termination of pregnancy in severe preeclampsia. Methods: The relationship between gestational age, delivery mode and perinatal outcome in 159 severe preeclampsia patients from 2000 to 2007 in Yichun People’s Hospital of Jiangxi Province was retrospectively analyzed. Results: The incidence of low birth weight in neonates born 32 to 36 + 6 weeks was significantly higher than those born 37 weeks after birth (P <0.01). The incidence of hyaline membrane disease was significantly different from that of those born 37 weeks after pregnancy ), But there was no significant difference in the survival rate between perinatal and postnatal 37 weeks (P> 0.05). Neonatal asphyxia and aspiration pneumonia were significantly higher in those born 37 weeks after birth than those born 32 to 36 + 6 weeks (P <0.05), and no significant difference in perinatal outcome between vaginal delivery and cesarean section Difference (P> 0.05). CONCLUSIONS: Patients with severe preeclampsia who have no significant improvement after active treatment may consider termination of pregnancy at 32-36 + 6 weeks of pregnancy. Patients with gestational age ≥37 weeks should terminate pregnancy as early as possible and choose vaginal delivery as appropriate Does not increase the risk of mother and child.