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[目的]评价石狮市中小学生接种乙肝疫苗后的抗体水平。[方法]对1 898名HBsAg和抗-HBs阴性的学生接种重组乙肝疫苗,免疫结束6个月后检测抗体。[结果]抗-HBs阳转率92.1%(1 749/1 898),小学生与中学生的抗-HBs阳转率差异显著(P<0.05)。[结论]中小学生接种乙肝疫苗免疫效果较好,随年龄的增大,免疫效果有下降趋势。应加强青少年乙肝疫苗接种,控制人群乙肝病毒感染。
[Objective] To evaluate the antibody level of primary and secondary school students in Shishi city after inoculation of hepatitis B vaccine. [Method] A total of 1 898 HBsAg and anti-HBs negative students were inoculated with recombinant hepatitis B vaccine and antibodies were detected 6 months after the end of immunization. [Results] The positive rate of anti-HBs was 92.1% (1 749/1 898). The positive rate of anti-HBs in primary and secondary school students was significantly different (P <0.05). [Conclusion] The primary and secondary school students vaccinated with hepatitis B vaccine have better immunization effect. With the increase of age, the immune effect has a declining trend. Hepatitis B vaccination should be strengthened to control the population of hepatitis B virus infection.