环己基苯基甲酮(1)是合成镇痉药苯基环己基甲醇的重要中间体[1],文献报道的合成方法主要有三种:一、羰基化反应。(1)碘苯与碘环己烷在Pd-Zn-Cu催化下与一氧化碳在50℃反应24h,碘苯的转化率为42%,1的收率为63%[2];(2)甲基环戊烷与苯在HF和SbF5作用下与一氧化碳于0～20℃反?.. Cyclohexyl phenyl ketone (1) is an important intermediate for the synthesis of antispasmodic phenylcyclohexylmethanol [1]. There are mainly three synthetic methods reported in the literature: one, carbonylation. (1) The iodobenzene and iodocyclohexane were reacted with carbon monoxide at 50 ℃ for 24 h under the catalysis of Pd-Zn-Cu. The conversion of iodobenzene was 42% and the yield of 1 was 63% [2]. Cyclopentane and benzene in the role of HF and SbF5 with carbon monoxide at 0 ~ 20 ℃ reversed?