研究显示,卵巢中可能存在具有自我更新和分化潜能的生殖干细胞,尽管数量很少,但能产生新的卵母细胞和维持始基卵泡发生。对生殖干细胞的分离培养及其分化调控的研究将会加深研究者对生殖生理的认识,并为保留卵巢恶性肿瘤患者的生育功能及对卵巢性不孕症的治疗提供新的策略。 Studies have shown that ovarian cells may have germline stem cells with self-renewal and differentiation potential, and may generate new oocytes and maintain primordial follicles, albeit in small numbers. Researches on the isolation, culture and differentiation regulation of germline stem cells will deepen the researchers’ understanding of reproductive physiology and provide new strategies for preserving fertility and treating ovarian infertility patients with ovarian cancer.