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目的 研究海尔福对砷中毒的疗效。方法 以健康的小白鼠作为研究对象 ,随机分成中毒治疗组 ( 1)、中毒对照组 ( 2 )、和正常对照组 ( 3 ) ,( 1) ( 2 )组用亚砷酸钠染毒 ,( 1)组用海尔福口服液治疗 ,治疗时间 3 0d ,结束取血测定各动物血清肌酐 (Cre)、血红蛋白 (Hb)、谷胱甘肽 (GSH)等生化指标。结果 各组肌酐分别为 ( 75 .75± 16.95、10 7.2 9± 2 6.88、79.92±16.48) μmol/L ;Hb分别为 ( 81.5± 2 .0 7、76.8± 2 .14、82 .6± 3 .2 7)g/L ;GSH分别为 ( 2 81.8± 3 .2 5、2 45 .1± 16.12、3 3 9.8± 2 3 .5 2 )mg/L。结论 砷中毒组血清肌酐升高、Hb和GSH降低 ,治疗组明显恢复
Objective To study the efficacy of Haier Fu on arsenic poisoning. Methods The healthy mice were randomly divided into two groups: poisoning treatment group (1), poisoning control group (2) and normal control group (3), (1) and (2) 1) group was treated with Haier Fu oral solution, the treatment time was 30 days, and the blood was collected to determine the serum creatinine (Cre), hemoglobin (Hb), glutathione (GSH) and other biochemical indexes. Results The levels of creatinine in each group were (75.75 ± 16.95,10 7.29 ± 2 6.88, 79.92 ± 16.48) μmol / L, respectively. The levels of Hb were (81.5 ± 2.07, 76.8 ± 2 .14, 82.6 ± 3 .2 7) g / L; GSH were (2 81.8 ± 3 .2 5,2 451 ± 16.12,3 3 9.8 ± 2 3 .5 2) mg / L, respectively. Conclusion Serum creatinine is elevated, arsenic poisoning group Hb and GSH decreased, the treatment group significantly recovered