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乙型肝炎病毒相关性肾炎是指乙型肝炎病毒感染引起的一种继发性肾小球性肾炎。HBV-GN的病因为HBV感染,其发病机制理尚未完全清楚,与遗传背景、免疫复合物介导、HBV直接感染及自身免疫紊乱等有关[1]。肾脏病理改变以膜性肾病最多见,其次是膜增生性肾炎,其他如弥漫增生性肾炎、IgA肾病、系膜增生性肾炎,局灶节段性肾小球硬化,局灶增生性肾炎,轻微病变及新月体肾炎等[2]。本文就HBV-GN的治疗进展作一综述如下:
Hepatitis B virus-associated nephritis refers to a type of secondary glomerulonephritis caused by hepatitis B virus infection. The cause of HBV-GN is HBV infection. The pathogenesis of HBV-GN is not yet completely understood, which is related to genetic background, immune complex-mediated, HBV direct infection and autoimmune disorders. Renal pathological changes to the most common membranous nephropathy, followed by membranoproliferative nephritis, other such as diffuse proliferative glomerulonephritis, IgA nephropathy, mesangial proliferative glomerulonephritis, focal segmental glomerulosclerosis, focal proliferative glomerulonephritis, mild Lesions and crescentic nephritis [2]. This article on the treatment of HBV-GN are reviewed as follows: