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精子表面的抗原与受精和胚胎的早期发育有密切关系,其中部分抗原能引起机体产生相应的抗体,从而影响到精子的受精功能和胚胎的发育,导致免疫性不育。因此对人类精子膜抗原的研究有助于从蛋白质水平来揭示受精的过程和不育的机制,为不育特别是免疫性不育的治疗及免疫避孕开辟一?
Antigen on the surface of sperm and fertilization and embryonic development are closely related to the early part of the antigen can cause the body to produce the corresponding antibodies, thus affecting the fertilization of sperm and embryonic development, resulting in immune sterility. Therefore, the study of human sperm membrane antigen helps to reveal the process of fertilization and the mechanism of infertility from the protein level, to open up one for the treatment of infertility, especially immune sterility and immune contraception?