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目的:探讨肺炎支原体感染诱发儿童哮喘的主要临床特征,以及与免疫蛋白E(Ig E)水平的相关性。方法:选取肺炎支原体感染诱发哮喘患儿47例作为观察组,将同期非感染性哮喘患儿53例作为对照组。分别比较两组儿童的MP抗体阳性率、Ig E水平以及临床特征,进行统计学分析。结果:观察组患儿的Mp抗体阳性率、Ig E水平均明显高于对照组,且本组患儿中发热、心肌酶异常与肝功能异常发生率也明显高于对照组,差异均有统计学意义(P<0.05)。结论:肺炎支原体感染诱发哮喘患儿通常具有明显临床特征,检测Mp抗体与Ig E水平可辅助临床诊断与治疗。
Objective: To investigate the main clinical features of childhood asthma induced by Mycoplasma pneumoniae and its relationship with the level of IgE. Methods: 47 cases of children with asthma induced by Mycoplasma pneumoniae infection were selected as the observation group, 53 cases of non-infected asthma children as the control group. The MP antibody positive rate, Ig E level and clinical features were compared between the two groups respectively for statistical analysis. Results: The positive rate of Mp antibody and IgE in the observation group were significantly higher than those in the control group, and the incidence of fever, myocardial enzyme abnormality and abnormal liver function were also significantly higher in the observation group than in the control group Significance (P <0.05). Conclusion: Mycoplasma pneumoniae infection in children with asthma usually have significant clinical features, detection of Mp antibody and Ig E levels can help clinical diagnosis and treatment.