为探明神经肽Ｙ（ＮＰＹ）受体在中枢神经系统的分布，用免疫组织化学方法，研究了ＮＰＹ－Ｙ１受体亚型免疫反应神经细胞及纤维在大鼠中枢神经系统的分布。结果表明，ＮＰＹ－Ｙ１受体免疫反应神经细胞或／和纤维在嗅结节、海马、屏状核、背侧丘脑诸核群、下丘脑弓状核、三叉神经感觉主核和脊束核等结构中分布密集，在额叶、颞叶、前嗅核、杏仁核等部位中也有较丰富的分布。提示ＮＰＹ－Ｙ１受体与嗅觉、躯体感觉和下丘脑的某些功能有着密切关系 To investigate the distribution of neuropeptide Y (NPY) receptors in the central nervous system, the distribution of NPY-Y1 receptor subtype immunoreactive nerve cells and fibers in the central nervous system of rats was studied by immunohistochemistry. The results showed that NPY-Y1receptor immunoreactive nerve cells and / or fibers could be found in olfactory nodules, hippocampus, platy nucleus, dorsal thalamic nuclei, hypothalamic arcuate nucleus, trigeminal sensory nucleus and spinal bundle nucleus Structure-intensive distribution, in the frontal lobe, temporal lobe, the former olfactory nucleus, amygdala and other parts of the more abundant distribution. It is suggested that the NPY-Y1 receptor is closely related to the sense of smell, somatosensory function and some functions of the hypothalamus