This is a translation report. The selected source text is a medical experimental report published in September 2018 on Immunobiology, an American academic joal. The content is about the experimental research process and results of AIDS vac?cine, and the target readers are immunologists. According to Newmarks text typology theory, the text intended to convey infor?mation to target readers belongs to informative text, and should be guided by communicative translation. Therefore, the translator completed the translation report under the theoretical guidance of Newmark communicative translation.