免疫疗法的效果,已通过各种主观和客观参数有所评价。如变应原皮试反应的缩小,以及总的和特异性IgE水平的变化。通过病人症状的得分来评价这种效果是最直接的办法。但这种得分往往受到各种因素的影响,尤其是变应原暴露量的变化。作者通过鼻抗原激发试验来研究休克器官——鼻粘膜的敏感性变化,同时估价在免疫治疗期间观察鼻粘膜敏感性降低最适宜的变应原浓度。 The effectiveness of immunotherapy has been evaluated by various subjective and objective parameters. Such as the reduction of the allergen skin test response, and changes in total and specific IgE levels. Evaluating this effect by the patient’s symptom score is the most straightforward way. However, this score is often affected by various factors, especially changes in allergen exposure. The authors studied nasal organ-nasal mucosal sensitivity changes by nasal antigen challenge test while evaluating the optimal concentration of allergen observed to reduce nasal mucosal sensitivity during immunotherapy.