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多抗甲素是从α-溶血性链球菌培养液提取的α-甘露聚糖肽类物质,具有促进造血细胞生长,增强免疫功能等生理活性。临床用于再生障碍性贫血的治疗及肿瘤辅助治疗等,均有较好疗效。这些实验结果及临床疗效的资料基本都是注射(ip或iv)给药观察到的。多抗甲素在治疗应用中常需较长时间连续用药,若能改用口服给药,将为临床治疗带来极大方便。本文报告多抗甲素经口给药的药理效应。
Poly-A is a α-mannan peptide extracted from α-hemolytic streptococcus, which has the functions of promoting hematopoietic cell growth and enhancing immune function. Clinical treatment of aplastic anemia and tumor adjuvant therapy, etc., have a good effect. The results of these experiments and the clinical efficacy of the information are basically injected (ip or iv) administration observed. Polyactin A in the treatment of applications often take a long time continuous medication, if switched to oral administration, will bring great convenience for clinical treatment. This article reports the pharmacological effects of oral administration of poly-A.