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目的:观察热毒宁联合单磷酸阿糖腺苷治疗手足口病的疗效。方法:选取89例手足口病患儿随机分为治疗组44例和对照组45例,治疗组给予热毒宁注射液及单磷酸阿糖腺苷治疗,对照组给予利巴韦林治疗,观察两组治疗有效率和临床症状及体征消退时间。结果:治疗组治疗有效率和临床症状及体征消退时间均优于对照组,差异有统计学意义。结论:热毒宁注射液联合单磷酸阿糖腺苷治疗小儿手足口病疗效好,值得基层医院临床推广使用。
OBJECTIVE: To observe the curative effect of heat attenuating combined with vidarabine monophosphate in the treatment of HFMD. Methods: A total of 89 HFMD children were randomly divided into treatment group (n = 44) and control group (n = 45). The treatment group was treated with Renduining injection and vidarabine monotherapy, while the control group was treated with ribavirin. The two groups of treatment efficiency and clinical symptoms and signs of regression time. Results: The treatment efficiency and clinical symptoms and signs of subsided time are better than the control group, the difference was statistically significant. Conclusion: The combination of Renduining injection of adenosine monophosphate treatment of children with hand foot and mouth disease is good, it is worth to promote the use of primary hospital.