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目的:提高多中心性成骨肉瘤的诊治水平。方法:对近15年国内报道的15例多中心性成骨肉瘤的临床资料进行回顾性分析。结果:本病好发于青少年,肿瘤累及多骨或单骨多处发病。血清碱性磷酸酶(AKP)检测可作为判定肿瘤发展程度的指标。治疗上以手术、化疗为主。该肿瘤具有高度侵袭性,预后较差。结论:提高对本病的认识,并根据临床表现作相应血AKP检查。早发现,早诊断,早手术是诊治该病的关键。
Objective: To improve the diagnosis and treatment of multicentric osteosarcoma. Methods: The clinical data of 15 cases of multicentric osteosarcoma reported in the past 15 years were analyzed retrospectively. Results: The disease occurs in adolescents, tumors involving multiple bones or multiple bone disease. Serum alkaline phosphatase (AKP) test can be used as an indicator of tumor development. Treatment to surgery, chemotherapy-based. The tumor is highly aggressive with poor prognosis. Conclusion: To improve the understanding of the disease, and according to clinical manifestations of the corresponding blood AKP examination. Early detection, early diagnosis, early surgery is the key to diagnosis and treatment of the disease.