论文部分内容阅读
目的应用磁共振成像(MRI)普通扫描及磁敏感加权成像序列(SWI)扫描了解脑立体定向干细胞移植治疗脑瘫后实际细胞移植靶点,了解两种扫描序列显示靶点的差异,为更好地显示移植靶点及为评估临床疗效提供影像学依据。方法 40例痉挛型脑瘫患儿,均行立体定向干细胞脑内基底节区移植,术后第1天行颅脑MRI普通扫描及SWI扫描,观察两种扫描序列显示实际细胞移植靶点的情况,比较两者显示靶点方面的差异。结果在所有患者中,应用常规扫描,在基底节区细胞移植靶点显影36例,4例未显影,显影率90%;在36例显影的患者中,其中28例与术前靶点吻合,8例部分吻合。应用SWI序列扫描基底节区细胞移植靶点显影38例,2例未显影,显影率95%。在38例显影的患者中,其中34例与术前靶点吻合,4例部分吻合。结论 SWI在显示实际移植靶点方面优于普通扫描序列。SWI可以作为术后显示移植靶点的首选方案,对显示实际移植靶点、评估靶点与疗效间的关系及积累相关临床经验具有积极的意义。
OBJECTIVE: To study the target of brain stem cells transplantation after brain stereotactic stem cell transplantation (STI) by using magnetic resonance imaging (MRI) plain scanning and magnetic resonance weighted imaging sequence (SWI) scanning to understand the difference between the two target sequences. Showing the target of transplantation and providing imaging evidence for evaluating clinical efficacy. Methods Forty children with spastic cerebral palsy underwent stereotactic stem cell transplantation in the basal ganglia. One day after operation, they were scanned with MRI and SWI scan. Two kinds of scanning sequences were used to show the actual target of cell transplantation. Compare the two to show differences in targets. Results In all the patients, 36 cases were developed at the target site of basal ganglionic cell transplantation by conventional scanning, and 4 cases were not developed, the developing rate was 90%. Of the 36 cases developed, 28 cases were consistent with preoperative target, 8 cases partially consistent. Thirty-eight cases were screened by SWI sequence scanning in basal ganglionic cell transplantation target, two cases were not developed, the developing rate was 95%. Of the 38 patients developed, 34 had anastomosis with the preoperative target and 4 had partial anastomosis. Conclusion SWI is superior to the normal scan sequence in displaying the actual target of transplantation. SWI can be used as the first choice of postoperative transplant target display, which has positive significance in displaying actual target of transplantation, assessing the relationship between target and effect and accumulating relevant clinical experience.