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目前市售的磺胺嘧啶或磺胺噻唑片剂,其含量一股都是0.5克,小孩服用时进行分割不易掌握准确剂量,而制成粉剂不仅费时,且服用亦不方便。如能制成混悬合剂則較好,因为一方面可使剂量准确,另一方面用糖漿作溶剂,小孩也乐于服用。但是由于混悬剂选擇的不当,影响混悬效力,有的在制备时虽能均匀分散,可是放置一些时候,就会分層沉下,甚至会發生粘瓶的現象,服用前須經長久用力振搖才能分散。作者等在生产实習过程中,在張楠森药师指导下,曾对該問題进行了試驗,初步获得了一些經驗,發現了比較理想的混悬剂,現將实驗記录写在下面,以供大家作进一步研究的参考。
Currently available sulfadiazine or sulfathiazole tablets, the content of a 0.5 grams are not easy to grasp when children take accurate dose, and made of powder is not only time-consuming, and taking is also not convenient. If made of suspension mixture is better, because on the one hand the dose can be accurate, on the other hand as a solvent with syrup, children are happy to take. However, due to improper suspension selection, affecting the suspension effect, while some can be evenly dispersed in the preparation, but when placed some time, it will stratify down, and even stick bottle phenomenon occurs, before taking long-term use of force Shake can be dispersed. The author in the production internship process, under the guidance of Zhang Nansen pharmacists, had conducted a test on the issue, initially obtained some experience and found the ideal suspension, the experimental record is now written below for everyone to make Reference for further research.