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目的观察曼月乐治疗子宫腺肌症的临床效果。方法子宫腺肌症患者58例,于月经第3~7天之间由专业医师按操作要求将曼月乐置入宫腔,术中经B超证实环位正常。放置曼月乐前及放置后1、3、6和12个月各随访1次,评估患者的痛经程度、月经量和子宫体积变化。结果3例发生治疗环脱落,未完成随访。与治疗前比较,放置曼月乐后3个月痛经减轻,VAS疼痛评分降低[(4.3±1.7)分vs.(8.2±1.6)分](P<0.01),月经量减少[(68±36)ml vs.(134±50)ml](P<0.01)。放置6个月后,子宫体积较治疗前缩小[(229±53)cm3 vs.(314±85)cm3](P<0.05)。结论采用曼月乐治疗子宫腺肌症能有效减轻患者痛经,减少月经量,缩小子宫体积;治疗期间的不良反应主要表现为不规则的点滴阴道出血,一般6个月后自行好转,无需特殊处理。
Objective To observe the clinical effect of Mirena treatment of adenomyosis. Methods Fifty-eight patients with adenomyosis were enrolled in the uterine cavity according to the operation requirements of the third and seventh days of menstruation. Place Mirenai before and 1, 3, 6 and 12 months after each visit to assess the degree of dysmenorrhea, menstrual flow and uterine volume changes. Results 3 cases of treatment ring off, did not complete follow-up. Compared with those before treatment, dysmenorrhea was relieved 3 months after Mirena was placed, VAS pain scores decreased (4.3 ± 1.7 vs 8.2 ± 1.6) (P <0.01), and menstrual flow decreased (68 ± 36 ) ml vs. (134 ± 50) ml] (P <0.01). After 6 months of implantation, the uterus volume was reduced (229 ± 53 cm3 vs 314 ± 85 cm3) compared with that before treatment (P <0.05). Conclusions The use of Mirena music in the treatment of adenomyosis can effectively reduce the patient dysmenorrhea, reduce menstrual flow, reduce the size of the uterus; adverse reactions during treatment mainly irregular vaginal bleeding, usually 6 months after the turn of the better, without special treatment .