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目的 观察 10例急性氟乙酰胺中毒者的心脏损害。方法 监测中毒者住院期间心肌酶和心电图的变化 ,同时采用动态心电图仪记录患者 2 4h动态心电图进行分析。结果 (1)治疗前有9例患者尿氟均有不同程度升高 ,治疗期间 10例患者均升高 ;(2 )住院期间全部病例心肌酶有 1项或多项异常 ;(3)入院时 4例心电图不正常 (含 2例窦缓 ) ,住院期间 5例为不正常心电图 (也有 2例窦缓 ) ,出院时全部为正常心电图 ;(4)动态心电图检查发现有 9例出现心脏电交替 ,1例游走心律 ,6例心律紊乱。结论 氟乙酰胺对心脏有明显的损害 ,而且可以引起心脏电交替。
Objective To observe the cardiac damage of 10 patients with acute fluoroacetamide poisoning. Methods The changes of myocardial enzymes and electrocardiogram (ECG) during hospitalization were monitored. The 24 h dynamic electrocardiogram was recorded by Holter monitor. Results (1) Before treatment, the urinary fluoride of 9 patients increased to varying degrees, and all 10 patients were elevated during the treatment. (2) One or more abnormalities of myocardial enzymes in all the cases during hospitalization; (3) 4 cases of abnormal electrocardiogram (including 2 cases of sinus bradycardia), 5 cases of abnormal ECG during hospitalization (there are 2 cases of sinus bradycardia), discharged at the time of all normal ECG; (4) Holter examination found that 9 cases of cardiac alternation , 1 case of walking heart rate, 6 cases of heart rhythm disorder. Conclusion Fluoroacetamide has obvious damage to the heart, and can cause the replacement of the heart.