组合化学已经成为药物开发和化学生物学的一种重要工具。它的进一步成功依赖于固相有机合成方法的深入发展。本文描述了合成杂环化合物及含氮杂环化合物的最近研究进展和一种有效的合成方法。 Combination chemistry has become an important tool for drug development and chemical biology. Its further success relies on the in-depth development of solid-phase organic synthesis methods. This article describes the recent progress of synthetic heterocyclic compounds and nitrogenous heterocyclic compounds and an effective synthesis method.