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为探讨老年急性白血病预后不良的原因 ,我们检测了 46例老年急性髓性细胞白血病 (AML)患者的多药耐药蛋白 (P-gp)表达。现报告如下。资料与方法 :本组男 2 7例 ,女 19例 ;年龄 6 0~ 78岁 ,平均 6 4岁。初发 2 4例 ,复发 2 2例。其中 M1 6例 ,M2 12例 ,M34例 ,M47例 ,M5 17例。
To investigate the causes of poor prognosis in elderly acute leukemia, we examined the expression of multidrug resistance protein (P-gp) in 46 elderly patients with acute myeloid leukemia (AML). The report is as follows. Materials and Methods: This group of 27 males and 19 females; aged 60-78 years old, average 6 4 years old. There were 24 patients with initial symptoms and 22 patients with recurrence. There were 6 cases of M1, 12 cases of M2, 34 cases of M4, M47 cases, and 17 cases of M5.