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目的:观察莫西沙星序贯疗法治疗成人衣原体肺炎的临床疗效和安全性。方法:将2008年5月-2012年12月我科收治的61例成人衣原体肺炎患者随机分为治疗组和对照组,治疗组31例采用莫西沙星治疗,对照组30例应用阿奇霉素治疗,疗程2周;比较两组的临床疗效及安全性。结果:治疗组总有效率为90.3%(28/31),显著高于对照组的63.3%(19/30);治疗组不良反应发生率16.1%(5/31)明显低于对照组的36.7%(11/30);P均<0.05。结论:莫西沙星序贯疗法治疗成人衣原体肺炎较阿奇霉素的疗效好,不良反应少。
Objective: To observe the clinical efficacy and safety of sequential treatment of moxifloxacin in adult patients with Chlamydia pneumonia. Methods: 61 cases of adult patients with Chlamydia pneumonia admitted in our department from May 2008 to December 2012 were randomly divided into treatment group and control group. 31 cases in the treatment group were treated with moxifloxacin and 30 cases in the control group were treated with azithromycin. The treatment course 2 weeks. The clinical efficacy and safety of the two groups were compared. Results: The total effective rate in the treatment group was 90.3% (28/31), significantly higher than 63.3% (19/30) in the control group. The incidence of adverse reactions in the treatment group was significantly lower than that in the control group (16.1%, 5/31) % (11/30); P <0.05. Conclusion: The sequential therapy of moxifloxacin is more effective than azithromycin in the treatment of adult chlamydial pneumonia, with less adverse reactions.