TiO2/graphene oxide(GO)as photocatalyst in the photo-degradation of multitudinous pol-lutants has been extensively studied.But its low photocatalytic efficiency is attributed to the high band gap energy which lead to low light utilization.Cu-TiO2/GO was synthesized via the impregnation methods to enhance the catalytic performance.The Cu-TiO2/GO reac-tion rate constant for photo-degradation of pollutants(tetracycline hydrochloride,TC)was about 1.4 times that of TiO2/GO.In 90 min,the removal ratio of Cu-TiO2/GO for TC was 98％,and the maximum degradation ratio occurred at pH 5.After five cycles,the removal ratio of Cu-TiO2/GO still exceeded 98％.UV-visible adsorption spectra of Cu-TiO2/GO showed that its band gap was narrower than TiO2/GO.Electron paramagnetic resonance(EPR)spectra test illustrated the generation rate of·O2-and·OH was higher in Cu-TiO2/GO system than TiO2/GO and TiO2 system.The contribution sequence of oxidative species was·O2-＞ holes(h+)＞·OH in both TiO2/GO and Cu-TiO2/GO system.Interestingly,the contribution of·OH in Cu-TiO2/GO was less than that in TiO2/GO during the photo-degradation process.This phe-nomenon was attributed to the better adsorption performance of Cu-TiO2/GO which could reduce the accessibility of TC to·OH in liquid.The enhanced non-hydroxyl radical contribu-tion could be attributed to that the more other active species or sites on(nearby)the surface of Cu-TiO2/GO generated after doping Cu.These results provide a new perspective for the tradition metal-doped conventional catalysts to enhance the removal of organic pollutants in the environment.