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目的优选痒宁颗粒的最佳提取工艺条件。方法采用单因素筛选法和正交设计法,进行提取工艺优选研究。结果挥发油提取最优工艺条件为药材加8倍水,浸泡0.5h,蒸馏6h;水提取最优工艺条件为A3B3C2,即煎煮2次,加12倍水,每次煎煮2h,结论优选得到的提取工艺简单、稳定、可行。
Objective To optimize the extraction process of itching granules. Methods Single factor screening and orthogonal design were used to optimize the extraction process. Results The optimum extraction conditions of volatile oil were medicinal materials plus 8 times of water, soaking for 0.5h and distillation for 6h. The optimum conditions of water extraction were A3B3C2, that is, boiling for 2 times and adding 12 times of water for 2h each time. The extraction process is simple, stable and feasible.