论文部分内容阅读
[目的]探讨化疗及手术干预对结直肠癌肝转移预后的影响。[方法]139例结直肠癌肝转移患者分为两组 ,肝动脉插管化疗组(HA)88例 ,全身静脉化疗组(SV)51例。术后3周开始化疗 ,4周1个疗程 ,共6个疗程。每1个疗程中 ,HA组丝裂霉素(MMC)20mg、5_Fu7g;SV组MMC10mg、5_Fu5.25g。术后随访3年 ,观察两组资料的1年、3年生存率。[结果]1年生存率HA组87.5%与SV组50.9%之间有极显著性差异(P<0.01) ,3年生存率HA组36.4%与SV组15%之间有极显著性差异(P<0.01)。[结论]结直肠癌肝转移手术后 ,肝动脉插管化疗的预后较全身静脉化疗好
[Objective] To investigate the effect of chemotherapy and operation intervention on the prognosis of liver metastasis from colorectal cancer. [Method] 139 cases of colorectal cancer with liver metastases were divided into two groups: hepatic arterial catheterization group (HA) 88 cases and systemic vein chemotherapy group (SV) 51 cases. 3 weeks after the start of chemotherapy, 4 weeks a course of treatment, a total of 6 courses. Each course of treatment, HA group mitomycin (MMC) 20mg, 5_Fu7g; SV group MMC10mg, 5_Fu5.25g. The patients were followed up for 3 years. The 1-year and 3-year survival rates of the two groups were observed. [Results] The 1-year survival rate was significantly different between 87.5% HA group and 50.9% SV group (P <0.01). The 3-year survival rate was significantly different between 36.4% HA group and 15% SV group P <0.01). [Conclusion] The prognosis of hepatic arterial catheterization after colorectal cancer liver transplantation is better than that of systemic vein chemotherapy