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目的探讨降钙素原(PCT)及传统炎症指标对儿童社区获得性肺炎(CAP)的诊断价值。方法回顾性分析呼吸道感染患儿277例,分为上呼吸道感染组(URI组,103例)和CAP组(174例),比较两组患儿呼吸道感染情况,分析PCT和炎症指标对呼吸道感染的诊断价值及CAP的影响因素。结果 CAP组患儿心率高于URI组(P<0.05)。URI组的WBC、中性粒细胞百分比(N%)、中性粒细胞计数(N)、PCT分别为13.58(9.23,20.31)×109/L、75.6(64.3,80.9)%、10.09(6.20,14.42)×109/L、0.125(0.073,0.386)ng/ml,均高于CAP组的10.13(7.22,15.34)×109/L、64.4(49.9,76.9)%、6.12(3.66,10.16)×109/L、0.078(0.046,0.189)ng/ml(P<0.01)。ROC曲线分析发现,PCT、WBC、N%、N对呼吸道感染有较高的诊断价值。N%是CAP的影响因素(P<0.05)。结论 PCT及传统炎症指标对呼吸道感染有较高的诊断价值,N%是CAP的影响因素。
Objective To investigate the diagnostic value of procalcitonin (PCT) and traditional inflammatory markers in children with community-acquired pneumonia (CAP). Methods A total of 277 children with respiratory tract infection were retrospectively analyzed. The patients were divided into upper respiratory tract infection group (URI group, 103 cases) and CAP group (174 cases). The respiratory infections in both groups were compared. Diagnostic value and influencing factors of CAP. Results The heart rate of CAP group was higher than that of URI group (P <0.05). The WBC, neutrophil percentage (N%), neutrophil count (N) and PCT were 13.58 (9.23,20.31) × 109 / L, 75.6 (64.3,80.9)%, 10.09 (6.20, 14.42) × 109 / L and 0.125 (0.073,0.386) ng / ml respectively, all of which were higher than that of CAP group (10.13 ± 7.22,15.34 × 109 / L, 64.4 ± 49.9,76.9%, 6.12 ± 3.66,10.16 × 109 /L, 0.078(0.046,0.189) ng / ml (P <0.01). ROC curve analysis found that PCT, WBC, N%, N of respiratory infections have a higher diagnostic value. N% is the influencing factor of CAP (P <0.05). Conclusion PCT and traditional inflammatory markers have higher diagnostic value for respiratory tract infections, and N% is the influencing factor of CAP.