目的探讨额下入路经眶小骨窗开颅显微手术治疗鞍区巨大型肿瘤的方法与疗效。方法对35例位于鞍内、鞍上并向鞍区周围部位侵袭生长的巨大型肿瘤采用一侧额下入路经眶小骨窗开颅显微手术切除。结果肿瘤显微镜下全切除27例,次全切除8例,无一例死亡,无严重并发症,恢复良好。结论此入路应用显微外科技术切除鞍区巨大型肿瘤均可做到显微镜下全切除或次全切除,具有操作简便,显露良好,创伤小的微创优点,是治疗鞍区巨大型侵袭性肿瘤较理想的手术入路。 Objective To investigate the method and effect of frontal subtotal craniotomy microsurgery for the treatment of huge tumors in the sellar region. Methods 35 cases of giant tumors located in the saddle, saddle and surrounding the saddle area were excised by microsurgery using the inferior frontal approach underwent craniotomy by orbital window. Results Tumor resection in 27 cases under microscope, subtotal resection in 8 cases, no case of death, no serious complications, recovery was good. Conclusion Microsurgical resection of giant tumor in the sect of this approach can be achieved under the microscope of subtotal or subtotal resection, which has the advantages of easy operation, good exposure and small trauma. More ideal surgical approach to the tumor.