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目的了解胆总管结石并胆道感染患者胆汁中主要致病菌的分布及其耐药情况。方法对本院2005年6月至2007年12月间收治的胆总管结石逆行内镜胰胆管造影术(ERCP)中抽取的胆汁标本进行细菌培养和药敏试验分布情况及耐药情况作回顾性分析。结果培养出109株细菌,革兰阴性杆菌86株(78.9%),大肠埃希菌37株(33.94%),肺炎克雷伯菌16株(14.68%);革兰阳性球菌22株(20.18%),其中肠球菌14株(14.84%);真菌属1株0.92%)。结论胆道感染主要病原菌是大肠埃希氏菌、肠球菌和肺炎克雷伯菌;对胆道细菌敏感的药物有亚胺培南、万古霉素、左旋氧氟沙星、头孢哌酮/舒巴坦、头孢他啶、阿米卡星。
Objective To understand the distribution and drug resistance of the main pathogens in the bile of patients with common bile duct stones and biliary tract infections. Methods We retrospectively analyzed the distribution and drug resistance of bile samples collected from ERCP in our hospital from June 2005 to December 2007 for bacterial culture and drug susceptibility testing analysis. Results A total of 109 strains of gram-negative bacilli were cultured, including 86 strains of Gram-negative bacilli (78.9%), 37 strains of Escherichia coli (33.94%), 16 strains of Klebsiella pneumoniae (14.68%), 22 strains of Gram- ), Of which 14 Enterococcus faecium (14.84%) and 1 fungus belonging to 0.92%). Conclusion The main pathogens of biliary tract infection are Escherichia coli, Enterococcus and Klebsiella pneumoniae. The drugs sensitive to biliary tract are imipenem, vancomycin, levofloxacin, cefoperazone / sulbactam , Ceftazidime, amikacin.