孕妇27岁。婚后连续发生3次孕龄2～3月的早期自然流产。本次妊娠5个月无胎动,阴道流血2天来院门诊,拟诊“过期流产”入院。夫妻非近亲婚配,否认遗传病家族史,无孕早期急性感染服药史,不嗜烟酒。体检:发育良好,营养中等,无重要脏器阳性病理体征。子宫前倾,宫颈光滑,宫口闭,宫体仅如孕2月 Pregnant woman 27 years old. 3 consecutive pregnancies occurred in 2 to 3 months of early spontaneous abortion. The 5-month pregnancy without fetal movement, vaginal bleeding 2 days to the hospital clinic, to be diagnosed “expired abortion ” admission. Couples non-relatives marriage, denied the family history of genetic disease, early pregnancy infection medication history, do not indulge alcohol and tobacco. Physical examination: well-developed, moderate nutrition, no important organs positive pathological signs. Uterine anteversion, smooth cervix, closed cervix, the uterus just as pregnant in February