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目的:分析左炔诺孕酮宫内缓释系统治疗子宫腺肌病的临床疗效。方法:回顾性分析我院2010年7月-2011年7月收治的46例子宫腺肌病患者,均采用左炔诺孕酮宫内缓释系统治疗,观察患者治疗前后的痛经程度、月经量以及子宫内膜的变化,评价该治疗方法的应用效果。结果:治疗后患者的痛经评分明显优于治疗前,月经量均较治疗前明显减少,子宫内膜厚度较治疗前明显变薄,差异均有统计学意义(P<0.05),治疗过程中部分患者有少量不规则阴道出血,均无严重不良反应发生。结论:左炔诺孕酮宫内缓释系统治疗子宫腺肌病能明显改善患者的痛经、月经量以及子宫内膜情况,效果明显,且安全性高,是临床治疗该疾病的首选治疗方案之一。
Objective: To analyze the clinical efficacy of levonorgestrel intrauterine system in the treatment of adenomyosis. Methods: A retrospective analysis of 46 cases of adenomyosis in our hospital from July 2010 to July 2011 were treated with levonorgestrel intrauterine system. The degree of dysmenorrhea and menstrual flow were observed before and after treatment As well as changes in the endometrium, evaluation of the therapeutic effect of the application. Results: After treatment, the score of dysmenorrhea in patients was significantly better than that before treatment and menstrual flow was significantly lower than before treatment. The thickness of endometrium was significantly thinner than that before treatment, with significant difference (P <0.05) Patients have a small amount of irregular vaginal bleeding, no serious adverse reactions. Conclusion: Levonorgestrel intrauterine system for the treatment of adenomyosis can significantly improve the patient’s dysmenorrhea, menstrual flow and endometrial conditions, the effect is obvious, and high safety, is the first choice of clinical treatment of the disease treatment options one.