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[目的]观察厚朴大黄汤联合西药治疗慢性阻塞性肺疾病急性期疗效。[方法]使用随机平行对照方法,将60例住院患者按就诊顺序编号简单随机分为两组。对照组30例头孢类、喹诺酮类抗感染,持续低流量吸氧,纠正酸碱水电解质紊乱等常规治疗,必要时予呼吸兴奋剂、支气管扩张剂等抢救措施。治疗组30例厚朴大黄汤加减(厚朴10g,大黄5~10g,炙麻黄6g,杏仁10g,生姜6g,杏仁10g,甘草15g,大枣10g;喘促气急加葶苈子15g;大量黄痰加黄芩、鱼腥草各10g;发热加金银花15g,连翘10g;双下肢水肿加茯苓25g,薏苡仁30g),水煎400m L,200m L/次,早晚温服;西药治疗同对照组。连续治疗15d为1疗程。观测临床症状、咳嗽、痰量、肺部啰音、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组显效19例,有效10例,无效1例,总有效率96.32%;对照组显效11例,有效11例,无效8例,总有效率33.25%;治疗组疗效优于对照组(P<0.05)[结论]厚朴大黄汤联合西药治疗慢性阻塞性肺疾病急性期,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Houpupulehuang Decoction combined with western medicine in acute phase of chronic obstructive pulmonary disease. [Methods] Using randomized parallel control method, 60 inpatients were randomly divided into two groups according to the order of their visits. Control group, 30 cases of cephalosporins, quinolones anti-infection, continuous low-flow oxygen, acid-base electrolyte to correct the disorders and other conventional treatment, if necessary, to respiratory stimulants, bronchodilators and other rescue measures. In the treatment group, 30 cases of Magnolia officinalis rhubarb decoction (Magnolia officinalis 10g, Rhubarb 5 ~ 10g, Sunburn ephedra 6g, almond 10g, ginger 6g, almond 10g, licorice 15g, jujube 10g; Yellow sputum plus skullcap, Houttuynia 10g; fever and honeysuckle 15g, forsythia 10g; double lower extremity edema plus Poria 25g, Coix Seed 30g), decoction 400m L, 200m L / times morning and evening warm clothes; Western medicine treatment with the control group. Continuous treatment of 15d for a course of treatment. Observation of clinical symptoms, cough, sputum volume, pulmonary rales, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] In the treatment group, 19 cases were markedly effective, 10 cases were effective, 1 case was ineffective, and the total effective rate was 96.32%. In the control group, 11 cases were markedly effective, 11 cases were effective, 8 cases were ineffective and the total effective rate was 33.25% (P <0.05) [Conclusion] HOPU combined with western medicine in the treatment of acute phase of chronic obstructive pulmonary disease, with satisfactory curative effect and no serious adverse reactions, should be popularized.