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目的了解合肥市耐多药肺结核可疑者筛查情况,探讨可疑者中耐多药/广泛耐药的相关因素。方法收集2012~2013年所有耐多药肺结核可疑者筛查数据,使用SPSS软件进行统计分析。结果全市共筛查耐多药肺结核可疑者344例,其中痰培养阳性114例(33.1%),登记为复治失败、其他、初治3月末涂阳的可疑者痰培养阳性率分别为66.7%、83.3%、16.7%。药敏试验结果为耐多药/广泛耐药病人46例(13.4%),多因素Logistic回归分析显示,60岁及以下、登记为复治失败或其他的可疑者耐多药/广泛耐药的检出率较高。结论合肥市耐多药结核病防治工作要加强重点人群的耐药检测,提高实验室痰培养阳性率。
Objective To understand the screening of suspicious MDR-TB patients in Hefei and to explore the relevant factors of MDR-MDR in suspicious persons. Methods The screening data of all MDR TB suspects from 2012 to 2013 were collected and analyzed by SPSS software. Results A total of 344 MDR-TB suspicious patients were detected in the city, of which 114 (33.1%) were positive for sputum culture and were registered as failed retreatment. The positive rate of sputum culture of the suspicious smear-positive children by the end of March was 66.7% , 83.3%, 16.7%. Susceptibility test results for 46 patients (13.4%) were resistant to MDR / MDR. Multivariate logistic regression analysis showed that patients aged 60 years and younger were registered as having failed multi-drug / extensive drug resistance The detection rate is higher. Conclusion The prevention and treatment of MDR-TB in Hefei should strengthen the drug resistance test in key populations and increase the positive rate of sputum culture in laboratory.