目的探讨新生儿惊厥的高危因素及防治措施。方法对148例有惊厥患儿及104例无惊厥患儿的情况进行成组资料的Logistic回归分析。结果有无缺氧缺血性脑病对新生儿惊厥的影响最大,其后依次是颅内出血、窒息程度和低钙血症。结论缺氧窒息后通过一系列机制引起惊厥,缺氧窒息是造成新生儿惊厥的主要原因。 Objective To investigate the risk factors and prevention and treatment measures of neonatal convulsion. Methods A total of 148 children with convulsion and 104 children without convulsion were analyzed by logistic regression. The results of whether hypoxic-ischemic encephalopathy has the greatest impact on neonatal seizures, followed by intracranial hemorrhage, asphyxia and hypocalcemia. Conclusion Hypoxia asphyxia causes convulsion after a series of mechanisms. Hypoxia and asphyxia are the main causes of neonatal convulsion.