转铁蛋白(transferrin,Tf)是一种非血红素结合铁的β-球蛋白,其N-端和C-端的两个同源结构域由一个短铰链区链接,每个结构域上含有一个铁离子结合位点,分别可逆结合一个Fe3+。转铁蛋白除具有结合、运输铁的功能外,还参与了呼吸、细胞增殖和免疫系统的调节等过程。因此,转铁蛋白是一类具有较全面生理功能的特殊蛋白质。 Transferrin (Tf) is a non-heme-bound iron beta-globulin whose two N-terminal and C-terminal homology domains are linked by a short hinge region, each containing one Iron ion binding sites, reversibly binding one Fe3 + respectively. Transferrin in addition to binding, transporting iron functions, but also involved in breathing, cell proliferation and immune system regulation process. Therefore, transferrin is a class of more comprehensive physiological function of the special protein.