目的 探讨T抗原单克隆抗体法在大肠癌筛检中的临床价值.方法 同时采用T抗原单克隆抗体法和半乳糖氧化酶法检测207例直肠粘液中的T抗原.结果 T抗原单克隆抗体法和半乳糖氧化酶法的敏感性和特异性分别为69.2%、67.3%和64.2%、65.6%,两者的筛检价值无明显差别.结论T抗原单克隆抗体法对大肠癌筛检有较大临床价值,且操作简便. Objective To investigate the clinical value of monoclonal antibodies against T antigen in colorectal cancer screening. Methods T antigen was also used to detect T antigen in rectal mucous from 207 monoclonal antibodies and galactose oxidase assay. Results T antigen monoclonal antibody method The sensitivity and specificity of the galactose oxidase assay were 69.2%, 67.3%, 64.2%, and 65.6%, respectively. There was no significant difference in the screening value between the two methods. Conclusions The monoclonal antibody against T antigen is more effective for colorectal cancer screening. Large clinical value and easy operation.