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目的:观察羧甲淀粉钠溶液佐治儿童哮喘的临床疗效。方法:186例支气管哮喘患儿分成两组各93例。治疗组在对照组治疗基础上加用羧甲淀粉钠溶液口服,同时比较治疗疗程、一个疗程(3个月)结束后,随访半年哮喘复发率及3个月后检测免疫功能进行比较。结果:治疗组总有效率77.42%,对照组总有效率38.71%。两组比较,差异有统计学意义(P<0.01)。治疗组平均病程及半年内哮喘复发率等数据均优于对照组(P<0.05或0.01)。治疗后,治疗组IgG、IgM、IgA明显升高(P<0.01),且升高幅度高于对照组(P<0.01)。结论:羧甲淀粉钠溶液能有效提高儿童哮喘患儿的免疫力,同时缩短其疗程及降低复发率。
Objective: To observe the clinical efficacy of sodium carboxymethyl starch solution in treating children with asthma. Methods: 186 children with bronchial asthma were divided into two groups of 93 cases each. The treatment group was treated with sodium carboxymethyl starch solution orally on the basis of the control group. At the same time, the course of the treatment was compared. After one course of treatment (3 months), the recurrence rate of asthma after 6 months and the immune function after 3 months were compared. Results: The total effective rate was 77.42% in the treatment group and 38.71% in the control group. The difference between the two groups was statistically significant (P <0.01). The average course of the treatment group and the recurrence rate of asthma within six months were better than the control group (P <0.05 or 0.01). After treatment, the levels of IgG, IgM and IgA in the treatment group were significantly increased (P <0.01), and the increases were higher than those in the control group (P <0.01). Conclusion: Sodium carboxymethyl starch solution can effectively improve the immunity of children with asthma, shorten the course of treatment and reduce the recurrence rate.