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目的：探讨老年癌症发生和免疫系统改变之间的关系。方法：测定５１例健康输血员和１２１例６０～８２岁老年癌症患者外周血中的Ｔ淋巴细胞亚群（ＣＤ３、ＣＤ４、ＣＤ８、ＣＤ４／ＣＤ８），红细胞免疫（ＲＢＣ—ＲＲ、ＲＢＣ—ＩＣＲ、ＣＩＣ）的变化，将两组测定结果对比。结果：老年恶性肿瘤患者免疫细胞及其功能比对照组明显下降，有非常显著性差别。结论：说明恶性肿瘤病程中确有红细胞免疫参与，老年恶性肿瘤的发生与老化过程中免疫系统的改变密切相关。
Objective: To explore the relationship between the occurrence of cancer in the elderly and the changes in the immune system. Methods: T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8), red blood cell immunity (RBC-RR, RBC-ICR) in peripheral blood of 51 healthy blood donors and 121 elderly patients aged 60-82 years were determined. Changes in CIC were compared between the two groups. Results: The immune cells and their functions in elderly patients with malignant tumors were significantly lower than those in the control group, with very significant differences. Conclusion: It shows that red blood cell immunity is involved in the course of malignant tumors. The occurrence of malignant tumors in the elderly is closely related to the changes of the immune system during aging.