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目的探讨青年和老年胃癌患者的临床病理特点与预后关系。方法1997年1月到2006年12月,有1362例胃癌患者在我院接受手术治疗,对其中32例青年(≤35岁)胃癌患者及188例老年(≥70岁)胃癌患者病理资料和随访资料进行回顾性比较分析。结果单因素分析显示,两组胃癌病人其预后与组织分化程度、浸润深度和淋巴结转移情况、年龄、进展期胃癌的大体类型均有相关性。应用Cox比例危险回归模型分析显示,肿瘤浸润深度和淋巴结转移情况、进展期胃癌的大体类型是影响胃癌病人术后生存的独立因素。结论肿瘤浸润深度和淋巴结转移情况、进展期胃癌的大体类型是影响胃癌病人术后生存的独立因素。
Objective To investigate the clinicopathological characteristics and prognosis of young and old patients with gastric cancer. Methods From January 1997 to December 2006, 1362 gastric cancer patients underwent surgical treatment in our hospital. Pathological data and follow-up of 32 young patients (≤35 years old) and 188 elderly patients (≥70 years old) with gastric cancer were retrospectively analyzed. Data were retrospectively analyzed. Results Univariate analysis showed that the prognosis of gastric cancer patients in both groups was correlated with the degree of tissue differentiation, depth of invasion, lymph node metastasis, age, and the general type of advanced gastric cancer. Cox proportional hazard regression model analysis showed that the depth of tumor invasion and lymph node metastasis, the general type of advanced gastric cancer is an independent factor affecting the survival of gastric cancer patients after surgery. Conclusion The depth of tumor invasion and lymph node metastasis, the general type of advanced gastric cancer is an independent factor affecting the survival of patients with gastric cancer.