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选择重庆市近郊农村学龄前儿童１４０名，男、女各半，随机分为单纯补锌组、补锌及复合微量营养素组和单纯补充微量营养素组，另一组为对照。实验组每组４０人，对照组为２０人，进行１０周营养干预实验。结果显示，在补锌的同时服用硒、锰、维生素Ａ等多种微量营养素或单纯补充多种微量营养素均能有效改善受试儿童体内锌营养状况，使血浆中前白蛋白、转铁蛋白、铜蓝蛋白含量增加，血清中多种必需及非必需氨基酸，３甲基组氨酸浓度下降。提示，儿童营养状况改善后其体内蛋白质合成代谢加强，而分解减少，这种变化除缘于血清锌含量增加外，可能还与其它微量营养素的作用有关。而单纯补锌儿童血清锌变化并不显著，血清中几种转运蛋白与对照均无明显差异。
A total of 140 preschoolers from rural Chongqing were enrolled, and were randomly divided into simple zinc supplementation group, zinc supplementation and compound micronutrient group and simple supplementation of micronutrient group, and the other group as control. The experimental group of 40 people in each group, the control group of 20 people, for 10 weeks of nutritional intervention experiments. The results showed that taking zinc, while taking a variety of micronutrients such as selenium, manganese, vitamin A, or simply adding a variety of micronutrients can effectively improve the nutritional status of zinc in children, so that plasma prealbumin, transferrin, Ceruloplasmin increased, a variety of essential and non-essential amino acids in serum, 3-methyl histidine concentration decreased. Prompted, after the improvement of children’s nutritional status of the body to enhance protein synthesis and metabolism, and reduce decomposition, in addition to the changes in serum zinc, may also be related to the role of other micronutrients. Serum zinc changes in children without zinc supplementation were not significant, and there were no significant differences in serum transport proteins and controls.