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目的 研究西安地区献血员中庚型肝炎病毒 (HGV)与乙型肝炎病毒 (HBV)、丙型肝炎病毒 (HCV)混合感染情况 .方法 采用 EL ISA方法检测献血员 34 2例血清中的 HBs Ag和抗 - HCV,用逆转录聚合酶反应 (RT- PCR)检测 HGV- RNA.结果 发现在西安地区 HBs Ag与抗 - HCV均为阴性的献血员中 HGV- RNA阳性率为 3.5 0 % (7/ 2 0 0 ) ,HBs Ag阳性 ,抗 -HCV阴性献血员中 HGV- RNA阳性率为 8.77% (5 / 5 7) ,HB-s Ag阴性而抗 - HCV 阳性献血员中 HGV- RNA阳性率为9.2 6 % (1 0 / 1 0 8) ,HBs Ag与抗 - HCV均为阳性的献血员 HGV-RNA阳性率为 1 5 .6 3% (5 / 32 ) .结论 HGV与 HBV和 (或 )HCV联合感染的阳性率要明显高于 HGV单独感染的阳性率
Objective To study the mixed infection of hepatitis G virus (HGV), Hepatitis B virus (HBV) and Hepatitis C virus (HCV) in blood donors in Xi’an area.Methods ELISA method was used to detect HBs Ag in blood serum of 34 2 donors And anti-HCV, HGV-RNA was detected by reverse transcription-polymerase chain reaction (RT-PCR) .Results showed that the positive rate of HGV-RNA in blood donors with negative HBsAg and anti-HCV in Xi’an was 3.5% / 2 0 0). The positive rate of HGV-RNA in HBs Ag positive and anti-HCV negative blood donors was 8.77% (5/57). The positive rate of HGV-RNA in HB-s Ag negative and anti-HCV positive blood donors (9.26% (10/18)). The positive rate of HGV-RNA in blood donors with positive HBsAg and anti-HCV was 15.36% (5/32) ) The positive rate of HCV co-infection was significantly higher than the positive rate of HGV infection alone