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目的探讨新生儿重度窒息及脑损伤后超声心动图的变化和临床意义。方法将2006-01—2006-12江西省宜春市人民医院40例重度窒息新生儿分为2组:单纯窒息组和窒息+脑损伤组(后者简称为脑损伤组)。另设20例正常新生儿为对照组。各组均在入院72h内完成心脏彩超检查。对脑损伤组治疗12~15d复查超声心动图。结果单纯窒息组、脑损伤组均表现为左室短轴缩短百分率(FS)下降,右室射血分数(RVEF)减低及右室射血前期与射血期比值(RVPEP/RVET)升高,尤以脑损伤组改变最为明显,其与对照组比较,差异有显著意义。脑损伤组经治疗后,心功能指标可基本恢复正常。结论超声心动图能早期观测重度窒息新生儿心功能的改变,合并了脑损伤的窒息新生儿心肌损伤更为严重。
Objective To investigate the changes and clinical significance of echocardiography in neonates with severe asphyxia and brain injury. Methods From January 2006 to December 2006, 40 newborns with severe asphyxia in Yichun People’s Hospital of Jiangxi Province were divided into two groups: simple asphyxia group and apnea + brain injury group (the latter referred to as brain injury group). Another 20 cases of normal newborn as a control group. All the groups completed cardiac echocardiography within 72h after admission. Echocardiography was performed on the brain injury group for 12-15 days. Results Asphyxia group and brain injury group showed decreased left ventricular fractional shortening (FS), decreased right ventricular ejection fraction (RVEF) and increased right ventricular ejection fraction and RVPEP / RVET, Especially in brain injury group changes the most obvious, compared with the control group, the difference was significant. Brain injury group after treatment, cardiac function can be basically returned to normal. Conclusion Echocardiography can early observe the changes of cardiac function in neonates with severe asphyxia, and myocardial injury in asphyxiated newborns with brain injury is more serious.