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慢性胃炎是由各种病因引起的胃黏膜慢性炎性反应。根据内镜及病理组织学改变,通常将慢性胃炎分为非萎缩性(浅表性)胃炎及萎缩性胃炎。前者是指胃黏膜层仅有淋巴细胞和浆细胞为主的浸润性改变,而无腺体萎缩;后者指胃黏膜腺体萎缩并常伴化生性改变(肠化或假幽门腺化生)。胃黏膜损伤和修复过程的演变,使慢性胃炎的病理组织变化多端,可表现为炎性反应、萎缩和化生,甚至异型增生。
Chronic gastritis is a chronic inflammatory reaction of the gastric mucosa caused by various causes. According to endoscopic and histopathological changes, chronic gastritis is usually divided into non-atrophic (superficial) gastritis and atrophic gastritis. The former refers to the gastric mucosa only lymphocytes and plasma cells-based infiltration of changes, but no gland atrophy; the latter refers to the gastric mucosal gland atrophy and often accompanied by metaplastic changes (intestinal metaplasia or pseudohypogonadal metaplasia) . Gastric mucosal injury and repair the evolution of the pathological changes in chronic gastritis multiple, can be manifested as inflammatory reaction, atrophy and metaplasia, and even dysplasia.