考虑到传统的疫苗设计（包括重组亚单位疫苗）似不能防御人类免疫缺陷症病毒（HIV）,携带单纯疱疹病毒胸苷激酶（TK）“自杀基因”的HIV减毒活疫苗的问世仅仅是时间问题。 为了安全地预防艾滋病,将疱疹病毒基因插入逆转录病毒,看来好象是通过迂回的途径来制备有效疫苗,但据从事此项研究的美国国立变态反应与传染病研究所（NIAID）的科学家说,他们的设计可能是给人们安全地接种HIV活疫苗的唯一方法。 Given that traditional vaccine designs (including recombinant subunit vaccines) do not seem to be able to defend the human immunodeficiency virus (HIV), the advent of live attenuated HIV vaccines carrying the herpes simplex virus thymidine kinase (TK) “suicide gene” is simply time problem. To safely prevent HIV, inserting the herpesvirus gene into a retrovirus appears to be a viable route for the preparation of an effective vaccine, but according to the scientists at the National Institute of Allergy and Infectious Diseases (NIAID) who conducted the study Said that their design may be the only way to give people safe vaccinations of HIV live vaccines.