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目的探讨双水平无创通气(Bi PAP)辅助治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的疗效。方法 80例COPD合并Ⅱ型呼吸衰竭的患者随机分为对照组和治疗组,各40例,对照组经常规抗感染、平喘、祛痰、吸氧等处理;治疗组在常规治疗基础上加Bi PAP无创呼吸机治疗。对比治疗后2、12、24、72 h两组患者的动脉血气和呼吸次数。结果治疗组患者在无创通气后不同时间段的血气分析中p H值、Pa O2、Pa CO2、呼吸次数较入院时有明显改善且差异有统计学意义(P<0.05)。而对照组与入院时比较研究指标改善不明显,差异无统计学意义(P>0.05)。结论使用无创呼吸机可有效改善COPD合并呼吸衰竭患者的血气及症状。
Objective To investigate the efficacy of bi-level noninvasive ventilation (Bi PAP) in the treatment of chronic obstructive pulmonary disease (COPD) complicated with type Ⅱ respiratory failure. Methods Eighty patients with COPD and type Ⅱ respiratory failure were randomly divided into control group and treatment group, 40 cases in each group. The control group was routinely treated with anti-infective, antiasthmatic, expectorant and oxygen-absorbing treatment. The treatment group was treated with routine treatment Bi PAP Noninvasive Ventilator Therapy. Arterial blood gas and respiratory rate were compared between two groups at 2, 12, 24 and 72 h after treatment. Results The values of p H, Pa O2, Pa CO2 and respiration in blood gas analysis at different periods after non-invasive ventilation were significantly improved in the treatment group compared with those at admission (P <0.05). The control group and admission comparative study indicators did not improve significantly, the difference was not statistically significant (P> 0.05). Conclusion The use of noninvasive ventilator can effectively improve the blood gas and symptoms of COPD patients with respiratory failure.